Fact Sheets Issued by PHA’s Scientific Leadership Council
Conventional Medical Therapies
- Calcium Channel Blockers – Help decrease blood pressure (Only appropriate for a small minority of patients demonstrating a favorable response to vasodilator testing at the time of heart catheterization.)
- Digoxin – Assists the pumping of the heart
- Diuretics – Rids excess fluid that puts pressure on the heart
- Oxygen – Inhaled by patients via a nasal cannula or face mask. Learn more about inhaled oxygen (O2) here.
- Warfarin (e.g. Coumadin®) – “Thins” blood and prevents it from clotting
Oral Treatment Options
Endothelin Receptor Antagonists (ERAs) help prevent blood vessels from narrowing.
Phosphodiesterase Inhibitors (PDE 5 Inhibitors) allow the lungs to produce more of its own natural vasodilators.
Prostacyclin Analogue allows the blood vessels in the lungs relax
Selective IP Receptor Agonist targets and activates a prostacyclin receptor which helps the blood vessels in the lungs relax.
Soluble Guanylate Cyclase (sGC) Stimulators increase the interaction of the sGC enzyme with another chemical (nitric oxide) to help the blood vessels in the lungs relax.
Inhaled Treatment Options
Inhaled Treatment Options, including prostacyclins, relieve shortness of breath.
Subcutaneous Treatment Options
Subcutaneous Treatment Options are delivered through a portable infusion pump to open up the blood vessels and ease the symptoms of PH.
Intravenous Treatment Options
Intravenous Treatment Options open up the blood vessels and help ease symptoms of PH, including chest pain and shortness of breath.
Research and Clinical Trials
Read about participating in research and clinical trials
Stem Cell Therapy
Read about stem cell therapy and PH
Visit our lung transplantation section