PHA Proof of Concept Award Winners
This grant’s target audience is investigators who are interested in early-stage pulmonary hypertension research.
This program supports new research projects that are in the early exploratory and developmental stages and have the potential to lead to advances in the scientific understanding of PH. Proposed projects result in preliminary data that will enable the investigator to apply for support for a larger, hypotheses-driven research project.
As of 2014, PHA has supported 13 researchers through this partnership and we hope to continue to further our understanding of PH by continuing to support such novel efforts in the field.
2016 |
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Kazuyo Kegan, PhD
“Illuminating AMPK function in crosstalk between Insulin Resistance and Pulmonary Hypertension” |
2015 |
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Ke Yuan, PhD
“The role of lung pericytes as a source of occluding pulmonary artery smooth muscle cells in PAH” |
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Soban Umar, MD, PhD
“Y Chromosome confers protection against pulmonary arterial hypertension” The Jerry Wojciechowski PH Proof of Concept Grant |
2014 |
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Daniel L. Fox, MD
“SSc-PAH Risk Score: Early Identification of Scleroderma-associated PAH by RV Strain, GDF-15 & IL&r” |
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Frances S. de Man, PhD
“A New Tool to Obtain Novel Insights in PAH-Induced Right Heart Failure” The Jerry Wojciechowski Pulmonary Hypertension Proof of Concept Grant |
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Fiona Murray, PhD
“A novel G-protein coupled receptor (GPCR) target in pulmonary arterial hypertension” American Thoracic Society Foundation/Pulmonary Hypertension Association Proof of Concept Research Grant |
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Marc de Perrot, MD, MSc
“Photodynamic therapy for the treatment of pulmonary arterial hypertension” |
2013 |
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Evan L. Brittain, MD
“Cardiac Steatosis and Right Ventricular Failure in Pulmonary Arterial Hypertension” |
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Jiwang Chen, PhD
“Role of IL7/IL7R in the Pathogenesis of Pulmonary Arterial Hypertension” |
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Kylie M. Drake, PhD
“Pharmacological Correction of BMP Signaling by Read-Through in Pulmonary Arterial Hypertension” The Jerry Wojciechowski Pulmonary Hypertension Proof of Concept Grant |
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Nicole M. Pohl, PhD
“Role of miR-181b in the Regulation of TRPC6 and the Development of Pulmonary Hypertension” |
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Yen-Rei Yu, MD, PhD
“The Role of Resident Monocytes in the Pathogenesis of Pulmonary Arterial Hypertension” |
2012 |
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Michael Yeager, PhD
“Unfolded Protein Response Confers Apoptosis Resistance and Inflammation in Pulmonary Hypertension” |
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Guofei Zhou, PhD
“AMPK and Pulmonary Arterial Hypertension” |
2011 |
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Mary Beth Brown, PhD, PT, ATC
“Clinical Investigation of a Daily Walking Program plus L-Arginine Supplementation for the Treatment of Pulmonary Arterial Hypertension” |
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Ferhaan Ahmad, MD, PhD
“Applying Genomics as a Springboard to Novel Mechanisms of Pulmonary Hypertension” |