PHA Proof of Concept Research Grant Winner 2014
Marc de Perrot, MD, MSc
Associate Professor of Surgery
University of Toronto, Canada
Title: “Photodynamic therapy for the treatment of pulmonary arterial hypertension”
Term: December 1, 2014- November 30, 2015
Summary of Research Project:
Dr. de Perrot’s objective is to determine the therapeutic effect of photodynamic therapy (PDT) on the treatment of experimental PAH animal models, which can be beneficial for the future clinical treatment of patients. He and his team believe that the current knowledge of PAH, as well as recent developments in high-powered laser and nanoparticles have opened the door for this new application of PDT. This grant will be used to provide the first evidence to support this concept. He and his team will use animal models as an immediate patient surrogate since PDT has never been used clinically and experimentally in treating PAH.