PHA Proof of Concept Research Grant Winner 2013
Nicole M. Pohl, PhD
Division of Pulmonary Medicine
University of Illinois at Chicago, Chicago
Title: “Role of miR-181b in the Regulation of TRPC6 and the Development of Pulmonary Hypertension”
Term: December 1, 2013- November 30, 2014
Summary of Research Project:
Idiopathic pulmonary arterial hypertension (IPAH) is a fatal, rare lung disease that primarily affects young women. Dr. Pohl will investigate the pathology of IPAH so that new therapies can be developed that treat the cause of the disease rather than its symptoms. This study will help us to understand how the disease develops and progresses. Once the mechanism of disease is understood, finding drugs that specifically target the misbehaving pathways becomes possible.