View an abstract from PHA’s 2017 PHPN Symposium to help you get started on your 2019 submission.
Prevalence of Right Ventricular Non-compaction: Single-Center Experience
Paulus S., Niebauer N., Freichels T., Zwicke D.
Aurora St. Luke’s Medical Center; Milwaukee
Determine prevalence of RV non-compaction in our clinic population.
Non-compaction of the left ventricle, characterized by prominent trabeculae with deep intertrabecular recesses in the ventricle, is well documented. The existence and prevalence of non-compaction of the right ventricle is documented but considered rare. However, in our clinical experience, with frequent detailed echo imaging of the right ventricle along with 3D imaging, RV non-compaction seems more prevalent than originally thought.
We prospectively reviewed echoes of patients evaluated in the pulmonary hypertension (PH) clinic from May 2014 through March 2017.
A total of 75 patients (mean age 65 [range 27-91]; 63 females (84.0%)) were found to have non-compaction of the right ventricle using 3D echo imaging. Sixteen of the 75 patients (21.3%) had biventricular non-compaction. Fifty three of 75 patients (71.0%) had WHO group I PAH, 1 patient (1.3%) had CTEPH, 17 patients (22.7%) had WHO group II PH (5 systolic dysfunction; 12 diastolic dysfunction), 1 patient (1.3%) had WHO group III PH (sleep disordered breathing), and 3 patients had no PH.
Based on our observations, RV non-compaction is more prevalent than originally thought. In our experience, careful assessment of the RV with 3D echo imaging has been the most useful tool to detect RV non-compaction. 3D echo imaging allows detection of increased trabeculae in the RV and differentiation from RV hypertrophy or the normal RV anatomy in patients. The significance of RV non-compaction in patient symptomatology and prognosis is unknown. Identifying RV non-compaction is important in the treatment of PAH patients as it may be mistaken for RVH resulting in over treatment with PAH vasodilator therapies.